Showing posts with label Gendicine. Show all posts
Showing posts with label Gendicine. Show all posts

Thursday, March 31, 2011

New Treatment Mesothelioma - Gendicine, The Latest Great Hope For Cancer and How to Seek Treatment

Gendicine works by combining the p53 gene, which is a tumor suppressant, with a utility virus. When the Gendicine virus is then injected into the cancerous tumor, the virus inserts the p53 gene into the cancer cells. Once the p53 gene is in the cancer cells, it causes them to self destruct. Clinical trials have shown a 64% success rate in this therapy combined with radiation therapy.

Dr. Li Dinggang is one of the men responsible for the success of this new therapy. He is an oncologist that studied for five years at the Johns Hopkins University during the 1990's. Since 1997, he has partnered with Dr. Peng Zhaohui, the chairman and CEO of the Chinese pharmaceutical company, SiBiono, to develop Gendicine. At 50 years old, Dr. Dinggang is the director of the Gene Therapy Center in China and also actively treats cancer patients at the Haidan Hospital in Beijing.

Mesothelioma New

Dr Dinggang requests that any cancer patients that are interested in Gendicine therapy submit their medical case histories in English and he will have it translated to Chinese. After reviewing the case history in Chinese, he will reply back with an assessment as to whether you should proceed to seek admission into the Haidan hospital for treatment.

New Treatment Mesothelioma - Gendicine, The Latest Great Hope For Cancer and How to Seek Treatment

It is advisable to seek out a friend or someone you know that is fluent in Chinese, to help with seeking admission to the hospital and basically communicating with the administration staff. Also, a Chinese translator would be very helpful in organizing local transportation and interim accommodation requirements while in Beijing.

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To obtain more information about Gendicine and contact information, visit: New Mesothelioma Treatment.

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Tuesday, November 9, 2010

Asbestos Mesothelioma - Gendicine, Could it Be the Next Promising Cure For Cancer?

Europe and the United States are probably still a year away from licensing gene therapy, however, there are currently at least two clinical trials testing gene therapy for mesothelioma. They include the University of Pennsylvania and the Louisiana State University. Unfortunately, gene therapy research took a big blow in 1999 when teenager Jesse Gelsinger died during a gene therapy clinical trial at the University of Pennsylvania.

Despite that, China is now the only country in the world that has already approved gene therapy. On October 16, 2003, the drug named Gendicine was approved by the State Food and Drug Administration of China. Gendicine had more than 5 years of clinical trials before it was approved. They have currently used this therapy on over 4500 patients and have followed their patient's progress for over 6 years. Now, hundreds of cancer patients from around the world are travelling to Beijing to receive this leading edge treatment.

The clinical trials of Gendicine included 135 patients and results showed that 64% of patients showed tumour regression after 8 weekly injections in combination with radiation therapy. According to the clinical trial results, using Gendicine with chemotherapy and radiation therapy can improve the efficacy by 3 times. The only side effect of Gendicine is a typical overnight fever.

Since there are no other approved gene therapy treatments in the world, many desperate cancer patients from North America and Europe are travelling to Beijing, China to receive treatment of Gendicine.

Richard Weissenborn from Texas, USA, had tongue cancer that had spread to his lymph nodes and was given two months to live in July of 2006. He was treated with Gendicine and chemotherapy by Dr. Li Dinggang at the Haidan Hospital in Beijing at a cost of about $30,000 U.S.

After two cycles of treatments, over two months, a pet scan showed that he was cancer free. The controversy around this story is that even though Richard's cancer was gone there are some doubts as to whether the chemotherapy or Gendicine cured it. Dr. Mark Persky, a cancer specialist remarked that "According to my review, there's really no way of telling whether one or the other caused tumour regression".

In a healthy cell, there is a gene called the p53 gene, which can repair DNA, arrest cell growth, and initiate a cellular self destruction if the cell damage is too great as in the case of cancer. However, in a study by the Chinese Academy of Preventive Medicine in Beijing, they found that there was a high occurrence of p53 gene damage in asbestos related cancers such as mesothelioma.

Gendicine works by reactivating the p53 gene, which acts as tumour suppressant but is shut off in a cancer cell because it may become deactivated by mutagens such as asbestos, chemicals and radiation. Gendicine treatment uses a virus as a medium to carry the p53 gene into the cancerous cells and causes the p53 gene to reactive and initiate self destruction (apoptosis) of the cancer cell.




Paul Folkmann is a mesothelioma cancer researcher. To learn more about gendicine, visit: New Mesothelioma Treatment. There you will also find information on mesothelioma treatments, stories of hope, and the latest news.

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