Sunday, October 18, 2009

Anti-Angiogenic Therapy - A New Approach To Mesothelioma

Introduction - What is Mesothelioma?

Mesothelioma, a cancer of the lining of the lungs, chest and abdominal attacks, is one of the most popular types of cancer in the world today. It is a fatal, incurable disease reported - some statistics show that 9 will die in 10 mesothelioma patients from the disease within 3 years. Only 5% survive more than 5 years after diagnosis.

Mesothelioma is caused by exposure to asbestos, a flexible,heat-resistant mineral fiber that was widely used in various industries, including shipbuilding, construction and mining encountered. Since the link between mesothelioma and asbestos was discovered to have numerous actions brought by victims against the company for the exposure. New laws to deal with asbestos came into force have been filed.

Since that time, research on potential mesothelioma treatment has continued, with varying results. Onethe newer therapies is being investigated as anti-angiogenesis-based therapies.

Angiogenesis

The term "anti-angiogenesis" comes from angiogenesis, a word that means the growth and development of new blood vessels. As cancers progress, they quickly outgrow the blood supply to them through the blood vessels of the body available and need to grow their own system of blood vessels to obtain an adequate supply of oxygen and nutrients. Without these new blood vessels, the cancer can not continue to grow and spread.

As anti-angiogenesis therapy Works

Anti-angiogenesis therapy is to prevent cancer cells to grow new blood vessels, thus slowing down or even stop the development of cancer. It does this by targeting the two chemicals in the body that regulate blood vessel growth: basic fibroblast growth factor (FGF-2) and vascular endothelial growth factor (VEGF). The latter chemical is particularly important> Mesothelioma patients, tests have shown that people with mesothelioma showing VEGF levels much higher than those of patients with other types of cancer. These results suggest that mesothelioma can have a strong binding to VEGF, and thus may be better to treatments that target VEGF.

One tested the experimental drug against mesothelioma is bevacizumab. This drug has been tested for use in patients with kidney, breast, ovary,and prostate, among others. Currently, the results of a study) in 2005 to the end, and compared the efficacy of bevacizumab against two chemotherapy drugs (gemcitabine and cisplatin, which are analyzed and not be released.

Whether anti-angiogenic therapy is a viable treatment or cure for mesothelioma remains to be seen. While scientists struggle to find new ways to fight mesothelioma, thousands of people continue to suffer from this devastatingDisease.

For more information on mesothelioma and asbestos, visit http://www.mesolawsuit.com for funds that the lawyers of Williams Kherkher mesothelioma made available.



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